ELISA test for the quantitative determination of Lactoferrin in stool samples. Increased Lactoferrin values are an indicator for:
- acute and chronic inflammatory bowel disease (IBD)
- Monitoring of Crohn´s disease and ulcerative colitis polyp excavation
Lactoferrin, is an alkaline polypeptide from neutrophil granulocytes, which is located in the intestinal mucosa and has an antibacterial function. Lactoferrin is a sensitive and very specific parameter for the detection of intestinal inflammation since Lactoferrin detected in the stool correlates with the migration of granulocytes from the intestinal wall into the intestinal lumen (Guerrant, Araujo et al. 1992). Lactoferrin can be used for monitoring of Crohn’s disease and ulcerative colitis (Kane, Sandborn et al. 2003, Kapral, Duller et al. 2004, Sipponen, Savilahti et al. 2008).
Main advantages:
- High stability allows time for convenient mailing of samples
- After reconstitution, standards and controls are stable for 10 weeks at 4-8 °C
- No weighing of the stool samples
- Incubation at room temperature
- Diluted stool extracts are stable for one week at 4-8 °