The new gold standard for non-invasive pancreatic function testing
Abdominal Pain – Maldigestion – Malassimilation – Chronic Pancreatitis – Cystic Fibrosis – Post-traumatic injuries
Is the pancreas involved?
The reliable and cost-effective ScheBo® • Pancreatic Elastase 1™ Stool Test gives you the answer.
The new gold standard!
The test is the new gold standard for non-invasive pancreatic function testing. It has been evaluated in comparisons with the invasive secretin-pancreozymin and secretin-caerulein tests.
Human pancreatic elastase 1 (E1) remains undegraded during intestinal transit. Therefore its concentration in faeces reflects pancreatic exocrine function. The diagnostic efficiency of pancreatic elastase 1 determination in stool has been evaluated in several clinical studies. Stein et al. (1993 & 1996, 1997) and Löser et al. (1995 & 1996) compared the E1 determination with invasive intubation tests, the secretin-pancreozymin test and the secretin-caerulein test, respectively. Both authors report a sensitivity and specificity greater than 90% for the diagnosis of exocrine pancreatic insufficiency. On contrast to the fecal chymotrypsin assay, even a moderate pancreatic insufficiency can be detected by E1 determination (Löser et al., 1995 & 1996, Gullo et al., 1999).
In addition, studies by Terbrack et al. (1996), Soldan et al. (1996), Gullo et al. (1999), Wallis et al. (1997), Walkowiak et al. (1999) and Cade et al. (2000) showed an excellent sensitivity and specificity for the diagnosis of cystic fibrosis with pancreatic involvement.
» The test
Further indications, advantages, reference concentration, specificity and sensitivity, method of detection, sample material, short protocol
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